| League Schedule | |
| Week 1 | |
| Matchup | Date/Score |
|---|---|
| West Virginia [pr] at Virginia Tech [ac] | Virginia Tech [ac] wins 35-28 |
| Texas [pr] at Ohio St. [ac] | Texas [pr] wins 27-10 |
| Missouri [pr] at South Carolina [ac] | Missouri [pr] wins 25-22 |
| Kansas St. [pr] at Tennessee [ac] | Tennessee [ac] wins 21-20 |
| Florida St. [ar] at Southern California [pc] | Southern California [pc] wins 42-30 |
| Notre Dame [ar] at Oklahoma [pc] | Notre Dame [ar] wins 43-36 |
| Clemson [ar] at Oklahoma St. [pc] | Clemson [ar] wins 38-35 |
| Cincinnati [ar] at Stanford [pc] | Stanford [pc] wins 41-20 |
| Michigan St. [ar] at Boise St. [pc] | Michigan St. [ar] wins 24-21 |
| Georgia [ar] at Oregon | Oregon wins 51-27 |
| Penn St. [ar] at Arkansas [pc] | Arkansas [pc] wins 28-25 |
| Florida [ar] at Baylor [pc] | Baylor [pc] wins 35-20 |
| Nebraska [pr] at Alabama [ac] | Nebraska [pr] wins 24-19 |
| Houston [pr] at LSU [ac] | Houston [pr] wins 55-29 |
| TCU [pr] at Michigan [ac] | Michigan [ac] wins 38-27 |
| Southern Miss. [pr] at Wisconsin [ac] | Wisconsin [ac] wins 34-28 |
| Week 2 | |
| Matchup | Date/Score |
| Arkansas [pc] at Florida [ar] | Arkansas [pc] wins 41-31 |
| Baylor [pc] at Penn St. [ar] | Baylor [pc] wins 31-29 |
| Alabama [ac] at TCU [pr] | Alabama [ac] wins 31-10 |
| LSU [ac] at Missouri [pr] | LSU [ac] wins 24-17 |
| Michigan [ac] at Southern Miss. [pr] | Michigan [ac] wins 43-35 |
| Wisconsin [ac] at Texas [pr] | Texas [pr] wins 17-14 |
| Virginia Tech [ac] at Kansas St. [pr] | Kansas St. [pr] wins 21-14 |
| Southern California [pc] at Notre Dame [ar] | Notre Dame [ar] wins 35-31 |
| Oklahoma [pc] at Florida St. [ar] | Florida St. [ar] wins 39-29 |
| Ohio St. [ac] at Nebraska [pr] | Nebraska [pr] wins 35-13 |
| South Carolina [ac] at West Virginia [pr] | South Carolina [ac] wins 35-30 |
| Tennessee [ac] at Houston [pr] | Houston [pr] wins 46-20 |
| Oklahoma St. [pc] at Georgia [ar] | Georgia [ar] wins 31-13 |
| Stanford [pc] at Michigan St. [ar] | Michigan St. [ar] wins 28-21 |
| Boise St. [pc] at Clemson [ar] | Boise St. [pc] wins 49-7 |
| Oregon at Cincinnati [ar] | Cincinnati [ar] wins 27-24 |
| Week 3 | |
| Matchup | Date/Score |
| Oklahoma St. [pc] at Ohio St. [ac] | Oklahoma St. [pc] wins 34-29 |
| Oklahoma [pc] at Michigan [ac] | Oklahoma [pc] wins 27-17 |
| Stanford [pc] at LSU [ac] | LSU [ac] wins 40-26 |
| Arkansas [pc] at Alabama [ac] | Alabama [ac] wins 48-27 |
| Boise St. [pc] at Tennessee [ac] | Boise St. [pc] wins 36-26 |
| Baylor [pc] at Virginia Tech [ac] | Baylor [pc] wins 34-13 |
| Oregon at Wisconsin [ac] | Wisconsin [ac] wins 27-14 |
| Houston [pr] at Georgia [ar] | Georgia [ar] wins 34-20 |
| Southern California [pc] at South Carolina [ac] | South Carolina [ac] wins 42-35 |
| Week 4 | |
| Matchup | Date/Score |
| Cincinnati [ar] at Houston [pr] | Houston [pr] wins 49-28 |
| LSU [ac] at Southern California [pc] | LSU [ac] wins 38-24 |
| Alabama [ac] at Oklahoma St. [pc] | Alabama [ac] wins 27-24 |
| South Carolina [ac] at Baylor [pc] | South Carolina [ac] wins 52-28 |
| Wisconsin [ac] at Oklahoma [pc] | Oklahoma [pc] wins 38-35 |
| Ohio St. [ac] at Oregon | Oregon wins 28-21 |
| Tennessee [ac] at Arkansas [pc] | Tennessee [ac] wins 31-27 |
| Virginia Tech [ac] at Stanford [pc] | Stanford [pc] wins 52-20 |
| Michigan [ac] at Boise St. [pc] | Boise St. [pc] wins 23-7 |
| Week 5 | |
| Matchup | Date/Score |
| Florida [ar] at Tennessee [ac] | Florida [ar] wins 38-37 |
| Michigan [ac] at Notre Dame [ar] | Notre Dame [ar] wins 34-24 |
| West Virginia [pr] at Oregon | Oregon wins 45-38 |
| Stanford [pc] at Kansas St. [pr] | Stanford [pc] wins 38-16 |
| Michigan St. [ar] at Wisconsin [ac] | Wisconsin [ac] wins 24-10 |
| Texas [pr] at Oklahoma [pc] | Oklahoma [pc] wins 30-0 |
| Florida St. [ar] at Alabama [ac] | Alabama [ac] wins 31-16 |
| Arkansas [pc] at Houston [pr] | Houston [pr] wins 26-14 |
| Nebraska [pr] at Southern California [pc] | Southern California [pc] wins 24-17 |
| Ohio St. [ac] at Cincinnati [ar] | Ohio St. [ac] wins 30-14 |
| South Carolina [ac] at Clemson [ar] | South Carolina [ac] wins 38-31 |
| Boise St. [pc] at TCU [pr] | TCU [pr] wins 26-20 |
| Baylor [pc] at Southern Miss. [pr] | Southern Miss. [pr] wins 56-23 |
| Virginia Tech [ac] at Penn St. [ar] | Virginia Tech [ac] wins 23-21 |
| Missouri [pr] at Oklahoma St. [pc] | Oklahoma St. [pc] wins 59-45 |
| Georgia [ar] at LSU [ac] | LSU [ac] wins 30-20 |
| Week 6 | |
| Matchup | Date/Score |
| Virginia Tech [ac] at Ohio St. [ac] | Virginia Tech [ac] wins 27-24 |
| Southern Miss. [pr] at Florida [ar] | Florida [ar] wins 37-36 |
| Houston [pr] at West Virginia [pr] | Houston [pr] wins 45-14 |
| LSU [ac] at South Carolina [ac] | South Carolina [ac] wins 24-21 |
| Boise St. [pc] at Arkansas [pc] | Boise St. [pc] wins 35-19 |
| Southern California [pc] at Baylor [pc] | Southern California [pc] wins 49-35 |
| Wisconsin [ac] at Michigan [ac] | Michigan [ac] wins 34-31 |
| Oregon at Oklahoma St. [pc] | Oregon wins 48-42 |
| Oklahoma [pc] at Stanford [pc] | Oklahoma [pc] wins 42-34 |
| Tennessee [ac] at Alabama [ac] | Alabama [ac] wins 38-6 |
| Week 7 | |
| Matchup | Date/Score |
| LSU [ac] at Michigan [ac] | LSU [ac] wins 33-7 |
| South Carolina [ac] at Virginia Tech [ac] | South Carolina [ac] wins 21-19 |
| Stanford [pc] at Boise St. [pc] | Boise St. [pc] wins 27-10 |
| Oklahoma St. [pc] at Arkansas [pc] | Oklahoma St. [pc] wins 42-23 |
| Southern Miss. [pr] at Georgia [ar] | Southern Miss. [pr] wins 21-14 |
| Alabama [ac] at Ohio St. [ac] | Alabama [ac] wins 28-16 |
| Kansas St. [pr] at Houston [pr] | Houston [pr] wins 41-38 |
| Tennessee [ac] at Wisconsin [ac] | Wisconsin [ac] wins 56-21 |
| Oklahoma [pc] at Baylor [pc] | Baylor [pc] wins 35-31 |
| Oregon at Southern California [pc] | Southern California [pc] wins 38-31 |
| Week 8 | |
| Matchup | Date/Score |
| Clemson [ar] at Southern Miss. [pr] | Southern Miss. [pr] wins 49-42 |
| Stanford [pc] at Southern California [pc] | Southern California [pc] wins 38-35 |
| Ohio St. [ac] at LSU [ac] | Ohio St. [ac] wins 37-34 |
| Kansas St. [pr] at West Virginia [pr] | West Virginia [pr] wins 37-31 |
| Boise St. [pc] at Oklahoma St. [pc] | Oklahoma St. [pc] wins 42-35 |
| TCU [pr] at Houston [pr] | Houston [pr] wins 42-25 |
| Arkansas [pc] at Oklahoma [pc] | Oklahoma [pc] wins 27-26 |
| Baylor [pc] at Oregon | Oregon wins 55-40 |
| Virginia Tech [ac] at Alabama [ac] | Alabama [ac] wins 34-10 |
| Michigan [ac] at Tennessee [ac] | Michigan [ac] wins 24-21 |
| South Carolina [ac] at Wisconsin [ac] | South Carolina [ac] wins 34-27 |
| Week 9 | |
| Matchup | Date/Score |
| Houston [pr] at Texas [pr] | Houston [pr] wins 38-28 |
| LSU [ac] at Virginia Tech [ac] | LSU [ac] wins 24-14 |
| Cincinnati [ar] at Southern Miss. [pr] | Cincinnati [ar] wins 33-20 |
| Oklahoma [pc] at Boise St. [pc] | Oklahoma [pc] wins 27-24 |
| Stanford [pc] at Baylor [pc] | Stanford [pc] wins 44-13 |
| Tennessee [ac] at Ohio St. [ac] | Ohio St. [ac] wins 34-21 |
| Oregon at Arkansas [pc] | Oregon wins 32-31 |
| South Carolina [ac] at Michigan [ac] | South Carolina [ac] wins 24-16 |
| Wisconsin [ac] at Alabama [ac] | Alabama [ac] wins 21-14 |
| Southern California [pc] at Oklahoma St. [pc] | Oklahoma St. [pc] wins 31-24 |
| Week 10 | |
| Matchup | Date/Score |
| Virginia Tech [ac] at Tennessee [ac] | Virginia Tech [ac] wins 28-20 |
| Oklahoma St. [pc] at Baylor [pc] | Oklahoma St. [pc] wins 59-38 |
| Southern Miss. [pr] at Houston [pr] | Houston [pr] wins 28-27 |
| Alabama [ac] at Michigan [ac] | Alabama [ac] wins 26-0 |
| Arkansas [pc] at Stanford [pc] | Stanford [pc] wins 37-29 |
| Southern California [pc] at Oklahoma [pc] | Oklahoma [pc] wins 35-32 |
| Boise St. [pc] at Oregon | Oregon wins 35-24 |
| Ohio St. [ac] at South Carolina [ac] | South Carolina [ac] wins 35-0 |
| Wisconsin [ac] at LSU [ac] | LSU [ac] wins 30-22 |
| Week 11 | |
| Matchup | Date/Score |
| LSU [ac] at Tennessee [ac] | LSU [ac] wins 19-13 |
| Houston [pr] at Clemson [ar] | Houston [pr] wins 59-38 |
| Baylor [pc] at Boise St. [pc] | Boise St. [pc] wins 28-21 |
| Michigan [ac] at Virginia Tech [ac] | Michigan [ac] wins 26-13 |
| Ohio St. [ac] at Wisconsin [ac] | Wisconsin [ac] wins 47-41 |
| Oklahoma [pc] at Oregon | Oklahoma [pc] wins 45-14 |
| Southern Miss. [pr] at Michigan St. [ar] | Michigan St. [ar] wins 24-16 |
| Alabama [ac] at South Carolina [ac] | Alabama [ac] wins 31-22 |
| Oklahoma St. [pc] at Stanford [pc] | Stanford [pc] wins 42-14 |
| Arkansas [pc] at Southern California [pc] | Southern California [pc] wins 38-12 |
| Week 12 | |
| Matchup | Date/Score |
| Oregon at Stanford [pc] | Stanford [pc] wins 38-35 |
| Wisconsin [ac] at Virginia Tech [ac] | Wisconsin [ac] wins 31-24 |
| Alabama [ac] at LSU [ac] | Alabama [ac] wins 16-14 |
| Southern California [pc] at Boise St. [pc] | Boise St. [pc] wins 42-40 |
| Houston [pr] at Nebraska [pr] | Houston [pr] wins 42-22 |
| Oklahoma St. [pc] at Oklahoma [pc] | Oklahoma [pc] wins 56-35 |
| Tennessee [ac] at South Carolina [ac] | South Carolina [ac] wins 21-10 |
| Michigan [ac] at Ohio St. [ac] | Michigan [ac] wins 28-0 |
| Texas [pr] at Southern Miss. [pr] | Southern Miss. [pr] wins 16-14 |
| Baylor [pc] at Arkansas [pc] | Arkansas [pc] wins 27-16 |